Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ALO39809.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 0.999
iscA
Iron-sulfur cluster assembly protein IscA; Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
 
 0.987
ALO40010.1
Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 0.972
iscR
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.969
ALO39671.1
Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.945
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.927
sufC
Fe-S cluster assembly ATPase SufC; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.865
erpA
Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters.
 
 
 0.842
sufB
Fe-S cluster assembly protein SufB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.792
sufD
Fe-S cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.792
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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