node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALO37468.1 | ALO39593.1 | UZ73_03810 | UZ73_15755 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.446 |
ALO37468.1 | gltA | UZ73_03810 | UZ73_05405 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.863 |
ALO37468.1 | mdh | UZ73_03810 | UZ73_05440 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.963 |
ALO37468.1 | modD | UZ73_03810 | UZ73_10085 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Modd protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.446 |
ALO37468.1 | nadB | UZ73_03810 | UZ73_17700 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.918 |
ALO37468.1 | purA | UZ73_03810 | UZ73_01875 | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.457 |
ALO38492.1 | argG | UZ73_09615 | UZ73_16485 | L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the asparaginase 1 family. | Argininosuccinate synthase; Catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | 0.916 |
ALO38492.1 | nadB | UZ73_09615 | UZ73_17700 | L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the asparaginase 1 family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.924 |
ALO38492.1 | panD | UZ73_09615 | UZ73_10265 | L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the asparaginase 1 family. | Aspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.939 |
ALO39593.1 | ALO37468.1 | UZ73_15755 | UZ73_03810 | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.446 |
ALO39593.1 | ALO39938.1 | UZ73_15755 | UZ73_17705 | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
ALO39593.1 | argG | UZ73_15755 | UZ73_16485 | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Argininosuccinate synthase; Catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | 0.441 |
ALO39593.1 | nadB | UZ73_15755 | UZ73_17700 | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.996 |
ALO39593.1 | panD | UZ73_15755 | UZ73_10265 | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Aspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.455 |
ALO39593.1 | purA | UZ73_15755 | UZ73_01875 | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.465 |
ALO39938.1 | ALO39593.1 | UZ73_17705 | UZ73_15755 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.999 |
ALO39938.1 | modD | UZ73_17705 | UZ73_10085 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Modd protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.978 |
ALO39938.1 | nadB | UZ73_17705 | UZ73_17700 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.999 |
argG | ALO38492.1 | UZ73_16485 | UZ73_09615 | Argininosuccinate synthase; Catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the asparaginase 1 family. | 0.916 |
argG | ALO39593.1 | UZ73_16485 | UZ73_15755 | Argininosuccinate synthase; Catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.441 |