node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GU3_07375 | GU3_08090 | GU3_07375 | GU3_08090 | COG0498 Threonine synthase. | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | 0.927 |
GU3_07375 | eutB | GU3_07375 | GU3_08040 | COG0498 Threonine synthase. | COG1171 Threonine dehydratase. | 0.961 |
GU3_07375 | ilvA | GU3_07375 | GU3_02380 | COG0498 Threonine synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.961 |
GU3_07375 | tdh | GU3_07375 | GU3_03240 | COG0498 Threonine synthase. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.901 |
GU3_08090 | GU3_07375 | GU3_08090 | GU3_07375 | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | COG0498 Threonine synthase. | 0.927 |
GU3_08090 | GU3_08145 | GU3_08090 | GU3_08145 | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.930 |
GU3_08090 | eutB | GU3_08090 | GU3_08040 | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | COG1171 Threonine dehydratase. | 0.918 |
GU3_08090 | ilvA | GU3_08090 | GU3_02380 | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.918 |
GU3_08090 | kbl | GU3_08090 | GU3_03235 | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.917 |
GU3_08090 | tdh | GU3_08090 | GU3_03240 | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.901 |
GU3_08145 | GU3_08090 | GU3_08145 | GU3_08090 | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Aromatic amino acid beta-eliminating lyase/threonine aldolase; COG2008 Threonine aldolase. | 0.930 |
GU3_08145 | GU3_10950 | GU3_08145 | GU3_10950 | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.558 |
GU3_08145 | bioF | GU3_08145 | GU3_09025 | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.536 |
GU3_08145 | fadJ | GU3_08145 | GU3_11625 | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Multifunctional fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.557 |
GU3_08145 | kbl | GU3_08145 | GU3_03235 | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.951 |
GU3_08145 | tdh | GU3_08145 | GU3_03240 | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.552 |
GU3_10950 | GU3_08145 | GU3_10950 | GU3_08145 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Sarcosine oxidase, subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.558 |
GU3_10950 | fadJ | GU3_10950 | GU3_11625 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Multifunctional fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.715 |
GU3_10950 | tdh | GU3_10950 | GU3_03240 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.478 |
GU3_11800 | tdh | GU3_11800 | GU3_03240 | COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.469 |