node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ampC | ampD | b4150 | b0110 | Penicillin-binding protein; This protein is a serine beta-lactamase with a substrate specificity for cephalosporins; Belongs to the class-C beta-lactamase family. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Is also involved in beta-lactamase induction ; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | 0.911 |
ampC | ampE | b4150 | b0111 | Penicillin-binding protein; This protein is a serine beta-lactamase with a substrate specificity for cephalosporins; Belongs to the class-C beta-lactamase family. | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | 0.809 |
ampC | ampG | b4150 | b0433 | Penicillin-binding protein; This protein is a serine beta-lactamase with a substrate specificity for cephalosporins; Belongs to the class-C beta-lactamase family. | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | 0.906 |
ampD | ampC | b0110 | b4150 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Is also involved in beta-lactamase induction ; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | Penicillin-binding protein; This protein is a serine beta-lactamase with a substrate specificity for cephalosporins; Belongs to the class-C beta-lactamase family. | 0.911 |
ampD | ampE | b0110 | b0111 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Is also involved in beta-lactamase induction ; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | 0.984 |
ampD | ampG | b0110 | b0433 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Is also involved in beta-lactamase induction ; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | 0.985 |
ampD | nadC | b0110 | b0109 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Is also involved in beta-lactamase induction ; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.756 |
ampE | ampC | b0111 | b4150 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Penicillin-binding protein; This protein is a serine beta-lactamase with a substrate specificity for cephalosporins; Belongs to the class-C beta-lactamase family. | 0.809 |
ampE | ampD | b0111 | b0110 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Is also involved in beta-lactamase induction ; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | 0.984 |
ampE | ampG | b0111 | b0433 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | 0.878 |
ampE | nadC | b0111 | b0109 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.709 |
ampE | opgC | b0111 | b1047 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | OPG biosynthetic transmembrane succinyltransferase; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. | 0.728 |
ampE | rcsD | b0111 | b2216 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division. | 0.686 |
ampE | tsgA | b0111 | b3364 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Putative transport; Belongs to the major facilitator superfamily. TsgA family. | 0.733 |
ampE | ycdY | b0111 | b1035 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.720 |
ampE | yeeA | b0111 | b2008 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Putative transporter, FUSC family inner membrane protein. | 0.752 |
ampE | yhfK | b0111 | b3358 | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process. | 0.755 |
ampG | ampC | b0433 | b4150 | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | Penicillin-binding protein; This protein is a serine beta-lactamase with a substrate specificity for cephalosporins; Belongs to the class-C beta-lactamase family. | 0.906 |
ampG | ampD | b0433 | b0110 | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Is also involved in beta-lactamase induction ; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. | 0.985 |
ampG | ampE | b0433 | b0111 | Muropeptide transporter; Permease involved in cell wall peptidoglycan recycling. Transports, from the periplasm into the cytoplasm, the disaccharide N-acetylglucosaminyl-beta-1,4-anhydro- N-acetylmuramic acid (GlcNAc-anhMurNAc) and GlcNAc-anhMurNAc-peptides. Transport is dependent on the proton motive force. AmpG is also involved in beta-lactamase induction ; Belongs to the major facilitator superfamily. | Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams. | 0.878 |