STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
maaMaltose o-acetyltransferase; Catalyzes the CoA-dependent transfer of an acetyl group to maltose and other sugars . Acetylates glucose exclusively at the C6 position and maltose at the C6 position of the non-reducing end glucosyl moiety. Is able to acetylate maltooligosaccharides (183 aa)    
Predicted Functional Partners:
Putative colanic acid biosynthesis pyruvyl transferase; Putative galactokinase; Protein involved in colanic acid biosynthetic process
Protein that modulates hha toxicity; Attenuates Hha toxicity and regulates biofilm formation. Binds to various coding and intergenic regions of genomic DNA
Haemolysin expression modulating protein; Down-regulates hemolysin (hly) expression in complex with H- NS . Stimulates transposition events in vivo . Modifies the set of genes regulated by H-NS; Hha and Cnu (YdgT) increase the number of genes DNA bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex . Binds DNA and influences DNA topology in response to environmental stimuli; does not however interact with DNA in the absence of H-NS . Involved in persister cell formation, acting downstream of mRNA interferase (toxin) MqsR . Decreases biofilm formation by [...]
[ribosomal protein s18]-alanine n-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18 . Also acts as a N-epsilon-lysine acetyltransferase that catalyzes acetylation of several proteins
3-methyl-adenine DNA glycosylase I, constitutive; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine from the damaged DNA polymer formed by alkylation lesions
4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family
annotation not available
Peptidyl-prolyl cis/trans isomerase (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized secretory and non-secretory proteins in an open conformation. Binds to 3 regions of unfolded substrate PhoA, preferring aromatic and hydrophobic residues, keeping it stretched out and unable to form aggregates . Binds to nascent polypeptide chains via ribosomal protein L23 . Functions as a peptidyl-prolyl cis-trans isomerase in vitro, this activity is dispensible in vivo for chaperone activity
Putative lipopolysaccharide biosynthesis o-acetyl transferase; Putative O-acetyltransferase that transfers an O-acetyl group to the O antigen
Maltodextrin glucosidase; May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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