STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfrABacteriophage n4 receptor, outer membrane protein; (Microbial infection) Allows N4 phage attachment by binding to the viral non-contractile sheath protein (990 aa)    
Predicted Functional Partners:
nfrB
Bacteriophage n4 receptor, inner membrane subunit; Required for bacteriophage N4 adsorption. May be a component of the phage receptor
 
   
 0.994
ybcH
annotation not available
 
 
   0.967
ymfA
annotation not available
  
     0.757
yfaL
Putative autotransporter adhesin yfal; Probably an autotransporter
  
   
 0.741
yfbM
annotation not available
  
     0.716
ydhQ
Autotransporter adhesin-related protein; Uncharacterized protein YdhQ; Possible enzyme
  
     0.693
yahC
annotation not available
  
     0.684
yliE
Putative membrane-anchored cyclic-di-gmp phosphodiesterase; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG (By similarity). Overexpression reduces biofilm formation. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria
  
     0.660
yjjJ
Putative protein kinase; Toxic when overexpressed in E.coli, leading to long filamentous cells. The toxic effect is neutralized by non-cognate antitoxin HipB . Does not seem to inhibit DNA, RNA or protein synthesis, and unlike paralogous toxin HipA its toxic activity is not counteracted by overexpression of GltX . Binds DNA . Might be a protein kinase (By similarity)
  
    0.657
sslE
Putative secreted and surface-associated lipoprotein mucinase; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane
  
  
 0.645
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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