STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mngBMannosylglycerate hydrolase; May hydrolyze 6-phospho-mannosyl-D-glycerate to mannose-6- phosphate and glycerate (877 aa)    
Predicted Functional Partners:
mngA
Fused 2-o-a-mannosyl-d-glycerate specific pts enzymes: iia component/iib component/iic component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . This system is involved in mannosyl- D-glycerate transport . Also involved in thermoinduction of ompC
 
   
 0.953
glxK
Glycerate 2-kinase 2; Belongs to the glycerate kinase type-1 family
  
 
  0.911
garK
Glycerate 2-kinase 1; Belongs to the glycerate kinase type-1 family
  
 
  0.911
mngR
Gntr family transcriptional regulator, mannosyl-d-glycerate transport/metabolism system repressor; Represses mngA and mngB. Regulates its own expression
 
  
 0.897
nagZ
Beta n-acetyl-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides
  
  
 0.635
yohF
Uncharacterized oxidoreductase YohF; Putative enzyme; Not classified; Belongs to the short-chain dehydrogenases/reductases (SDR) family
   
  
 0.613
ycbZ
Putative atp-dependent protease ycbz; Putative ATP-dependent protease; Protein involved in proteolysis
      
 0.588
yihQ
Putative sulpholipid alpha-glucosidase; Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E.coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur. Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids. Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro). Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ . Also exhibits some alpha-glucosi [...]
 
   
 0.577
agaS
Putative galactosamine-6-phosphate deaminase/isomerase; Catalyzes the isomerization-deamination of galactosamine 6- phosphate to form tagatofuranose 6-phosphate and ammonium ion
 
   
 0.572
ompL
Oligogalacturonate-specific porin family protein; Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown
 
     0.513
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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