node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
elyC | mukB | b0920 | b0924 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | Chromosome condensin mukbef, atpase and dna-binding subunit; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV | 0.593 |
elyC | mukE | b0920 | b0923 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | Chromosome condensin mukbef, muke localization factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF | 0.594 |
elyC | mukF | b0920 | b0922 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | Chromosome condensin mukbef, kleisin-like subunit, binds calcium; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity | 0.594 |
elyC | nanS | b0920 | b4309 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | 9-O-acetyl-N-acetylneuraminic acid deacetylase; Probably catalyzes the hydrolysis of the 9-O-acetyl group of 9-O-acetyl-N-acetylneuraminate (Neu5,9Ac2). Is required for growth of E.coli on Neu5,9Ac2, an alternative sialic acid commonly found in mammalian host mucosal sites, in particular in the human intestine | 0.575 |
elyC | sanA | b0920 | b2144 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | DUF218 superfamily vancomycin high temperature exclusion protein; Participates in the barrier function of the cell envelope | 0.603 |
elyC | smtA | b0920 | b0921 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | Putative s-adenosyl-l-methionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. Four tRNAs (tRNA(Ala1), tRNA(Ser1), tRNA(Pro3) and tRNA(Thr4)) are fully modified with mcmo5U in stationary-phase E.coli. Also present at low frequency in tRNA(Leu3) and tRNA(Val1) | 0.610 |
elyC | ydcF | b0920 | b1414 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | DUF218 superfamily protein, SAM-binding; Binds S-adenosyl-L-methionine (AdoMet) | 0.785 |
elyC | yfgG | b0920 | b2504 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | annotation not available | 0.520 |
elyC | ygjQ | b0920 | b3086 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | annotation not available | 0.825 |
elyC | yniB | b0920 | b1726 | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | annotation not available | 0.618 |
mukB | elyC | b0924 | b0920 | Chromosome condensin mukbef, atpase and dna-binding subunit; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | 0.593 |
mukB | mukE | b0924 | b0923 | Chromosome condensin mukbef, atpase and dna-binding subunit; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV | Chromosome condensin mukbef, muke localization factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF | 0.999 |
mukB | mukF | b0924 | b0922 | Chromosome condensin mukbef, atpase and dna-binding subunit; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV | Chromosome condensin mukbef, kleisin-like subunit, binds calcium; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity | 0.999 |
mukB | sanA | b0924 | b2144 | Chromosome condensin mukbef, atpase and dna-binding subunit; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV | DUF218 superfamily vancomycin high temperature exclusion protein; Participates in the barrier function of the cell envelope | 0.417 |
mukB | smtA | b0924 | b0921 | Chromosome condensin mukbef, atpase and dna-binding subunit; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV | Putative s-adenosyl-l-methionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. Four tRNAs (tRNA(Ala1), tRNA(Ser1), tRNA(Pro3) and tRNA(Thr4)) are fully modified with mcmo5U in stationary-phase E.coli. Also present at low frequency in tRNA(Leu3) and tRNA(Val1) | 0.969 |
mukE | elyC | b0923 | b0920 | Chromosome condensin mukbef, muke localization factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF | Envelope biogenesis factor; Plays a critical role in the metabolism of the essential lipid carrier used for cell wall synthesis | 0.594 |
mukE | mukB | b0923 | b0924 | Chromosome condensin mukbef, muke localization factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF | Chromosome condensin mukbef, atpase and dna-binding subunit; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV | 0.999 |
mukE | mukF | b0923 | b0922 | Chromosome condensin mukbef, muke localization factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF | Chromosome condensin mukbef, kleisin-like subunit, binds calcium; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity | 0.999 |
mukE | sanA | b0923 | b2144 | Chromosome condensin mukbef, muke localization factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF | DUF218 superfamily vancomycin high temperature exclusion protein; Participates in the barrier function of the cell envelope | 0.482 |
mukE | smtA | b0923 | b0921 | Chromosome condensin mukbef, muke localization factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF | Putative s-adenosyl-l-methionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. Four tRNAs (tRNA(Ala1), tRNA(Ser1), tRNA(Pro3) and tRNA(Thr4)) are fully modified with mcmo5U in stationary-phase E.coli. Also present at low frequency in tRNA(Leu3) and tRNA(Val1) | 0.995 |