STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gfcDannotation not available (698 aa)    
Predicted Functional Partners:
gfcC
Putative o-antigen capsule production periplasmic protein; To E.coli YjbG
  
 0.997
gfcB
O-antigen capsule production lipoprotein; Uncharacterized lipoprotein GfcB; Putative regulator
 
  
 0.994
gfcE
Putative o-antigen capsule outer membrane auxillary protein export channel; May be involved in polysaccharide transport
 
 
 0.980
etp
O-antigen capsule forming protein-tyrosine-phosphatase; Dephosphorylates etk
 
 
 0.956
etk
Tyrosine-protein kinase, role in o-antigen capsule formation; Belongs to the etk/wzc family
 
 
 
 0.947
gfcA
annotation not available
     
 0.920
yjbG
Extracellular polysaccharide export oma protein; To E.coli YmcB
    0.820
yjbF
annotation not available
 
    0.777
ylbF
Putative anaerobic allantoin catabolic oxamate carbamoyltransferase; Uncharacterized protein YlbF; Putative carboxylase
      
 0.700
nuoC
Nadh:ubiquinone oxidoreductase, fused cd subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
  
 
 0.690
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.