STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yciCannotation not available (247 aa)    
Predicted Functional Partners:
yciB
Ispa family inner membrane protein; Involved in cell division; probably involved in intracellular septation
 
    0.930
yjiA
P-loop guanosine triphosphatase; Binds GTP and has low GTPase activity. May have a GTP- dependent regulatory function
      
 0.814
yqhA
annotation not available
      
 0.740
yeiR
Zn-stimulated gtpase involved in zinc homeostasis; Involved in metal homeostasis. Has GTPase activity. Binds several Zn(2+) ions in vitro
      
 0.731
yajG
Uncharacterized lipoprotein YajG; Putative polymerase/proteinase
  
    0.727
argK
Methylmalonyl-coa mutase-interacting gtpase ygfd; Binds and hydrolyzes GTP . Likely functions as a G-protein chaperone that assists AdoCbl cofactor delivery to the methylmalonyl-CoA mutase (MCM) ScpA and reactivation of the enzyme during catalysis
      
 0.706
yiiQ
annotation not available
  
     0.690
lpoB
Outer membrane lipoprotein - activator of mrcb activity; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Stimulates transpeptidase and transglycosylase activities of PBP1b in vitro. May also contribute to outer membrane constriction during cell division, in complex with PBP1b
  
     0.682
yoaE
Putative membrane protein/conserved protein; UPF0053 inner membrane protein YoaE; Putative transport protein
  
   
 0.677
yrfF
Inner membrane protein - inhibits the rcs signaling pathway; Putative membrane protein IgaA homolog; Putative dehydrogenase
  
     0.651
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.