STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uspEUniversal stress protein with a role cellular motility; Required for resistance to DNA-damaging agents (316 aa)    
Predicted Functional Partners:
uspF
Nucleotide binding filament protein; Universal stress protein F; Pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related
   
  
 0.926
uspD
Universal stress protein d; Required for resistance to DNA-damaging agents
   
  
 0.916
uspG
Universal stress protein up12; Has intrinsic autoadenylation and autophosphorylation activities, probably on Ser or Thr residues
   
 
 0.915
uspC
Universal stress protein c; Required for resistance to DNA-damaging agents
   
  
 0.894
uspA
Universal stress global stress response regulator; Required for resistance to DNA-damaging agents
   
  
 0.881
ynaJ
annotation not available
      
 0.790
uspB
Putative universal stress (ethanol tolerance) protein b; Belongs to the universal stress protein B family
   
  
 0.756
fnr
Crp/fnr family transcriptional regulator, anaerobic regulatory protein; Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration
  
  
 0.750
yfbV
annotation not available
  
    0.705
nlpI
Lipoprotein involved in osmotic sensitivity and filamentation; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division. Negatively controls the production of extracellular DNA (eDNA)
  
     0.664
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.