STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yddGAromatic amino acid exporter; Probable efflux pump. Overexpression confers resistance to phenylalanine and increases export of phenylalanine, tyrosine and tryptophan (293 aa)    
Predicted Functional Partners:
ytfF
Dmt transporter family inner membrane protein; Inner membrane protein YtfF; Putative transmembrane subunit
  
   
 0.848
leuE
Leucine efflux protein; Exporter of leucine. Can also transport its natural analog L- alpha-amino-n-butyric acid and some other structurally unrelated amino acids
      
 0.813
alaE
Alanine exporter, alanine-inducible, stress-responsive; Exports L-alanine
  
   
 0.808
osmB
Osmotically and stress inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival
 
     0.774
rhtA
Involved in the efflux of threonine and homoserine. Can also export other amino acids such as proline, serine, histidine and cysteine
  
   
 0.691
aroP
Aromatic amino acid transport protein arop; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan)
      
 0.620
fdnG
Formate dehydrogenase-n, alpha subunit, nitrate-inducible; Formate dehydrogenase allows E.coli to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor. The alpha subunit FdnG contains the formate oxidation site. Electrons are transferred from formate to menaquinone in the gamma subunit (FdnI), through the 4Fe-4S clusters in the beta subunit (FdnH). Formate dehydrogenase-N is part of a system that generates proton motive force, together with the dissimilatory nitrate reductase (Nar)
     
 0.590
yijF
annotation not available
      
 0.569
ybgQ
Putative fimbrial usher protein ybgq; Could be involved in the export and assembly of the putative YbgD fimbrial subunit across the outer membrane
      
 0.561
eamA
Cysteine and o-acetyl-l-serine efflux system; May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L- serine (OAS)), and for other amino acids and their metabolites
      
 0.561
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (3%) [HD]