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STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
ydeMPutative anaerobic sulfatase maturation enzyme ydem; Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family (385 aa)    
Predicted Functional Partners:
Putative cys-type oxidative yidj-maturating enzyme; Uncharacterized protein YidF; Putative transcriptional regulator
Putative ser-type periplasmic non-aryl sulfatase; Belongs to the sulfatase family
Asp/glu_racemase family protein; Amino-acid racemase able to utilize a broad range of substrates. Highest activity is observed with L-homoserine and D- homoserine. Has tenfold lower activity against L-methionine, L-leucine, L-valine and L-histidine. Has low activity with L-norvaline, L- asparagine, D-methionine, L-aminobutyric acid, L-isoleucine, L-serine, L-norleucine, L-alanine, L-glutamine, LL-diaminopimelic acid and L- phenylalanine. Has no activity against ten L-amino acids (Thr, Glu, Asp, Arg, Lys, Tyr, Trp, Orn, Cit and Aad) . D-amino acids might be used as components of peptido [...]
Galactofuranose abc transporter periplasmic binding protein; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Binds to both alpha- and beta- galactofuranose
Mfs transporter, sp family, arabinose:h+ symporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system)
Putative ser-type periplasmic non-aryl sulfatase; No E.coli strains have been observed to have an arylsulfatase activity. A 'latent' activity has been observed by heterologous expression of a genomic region linked to tynA, but it does not map near aslA
Sulfatase/phosphatase superfamily protein; Belongs to the sulfatase family
L-ribulose-5-phosphate 4-epimerase AraD; Involved in the degradation of L-arabinose . Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction)
Dna polymerase ii; Thought to be involved in DNA repair and/or mutagenesis. Its processivity is enhanced by the beta sliding clamp (dnaN) and clamp loader
Vitamin b12/bleomycin/antimicrobial peptide transport system atp-binding/permease protein; Inner membrane ABC transporter ATP-binding protein YddA; Putative transport; Not classified
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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