node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
chbR | marA | b1735 | b1531 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Multiple antibiotic resistance transcriptional regulator; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | 0.469 |
chbR | rclR | b1735 | b0305 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | 0.475 |
chbR | rhaR | b1735 | b3906 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Transcriptional activator of rhaSR; Activates expression of the rhaSR operon in response to L- rhamnose. | 0.870 |
chbR | rob | b1735 | b4396 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Right oriC-binding transcriptional activator, AraC family; Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication. | 0.480 |
chbR | soxS | b1735 | b4062 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Superoxide response regulon transcriptional activator; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters. | 0.540 |
chbR | ydiP | b1735 | b1696 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Putative ARAC-type regulatory protein; Protein involved in transcription and regulation of transcription, DNA-dependent. | 0.679 |
chbR | yidL | b1735 | b3680 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.679 |
frlR | ydiM | b3375 | b1690 | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | Putative MFS transporter, membrane protein; Putative transport system permease protein. | 0.522 |
frlR | ydiP | b3375 | b1696 | Putative DNA-binding transcriptional regulator; May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine. | Putative ARAC-type regulatory protein; Protein involved in transcription and regulation of transcription, DNA-dependent. | 0.690 |
marA | chbR | b1531 | b1735 | Multiple antibiotic resistance transcriptional regulator; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | 0.469 |
marA | rclR | b1531 | b0305 | Multiple antibiotic resistance transcriptional regulator; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | 0.734 |
marA | rhaR | b1531 | b3906 | Multiple antibiotic resistance transcriptional regulator; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Transcriptional activator of rhaSR; Activates expression of the rhaSR operon in response to L- rhamnose. | 0.809 |
marA | ydiP | b1531 | b1696 | Multiple antibiotic resistance transcriptional regulator; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Putative ARAC-type regulatory protein; Protein involved in transcription and regulation of transcription, DNA-dependent. | 0.748 |
marA | yidL | b1531 | b3680 | Multiple antibiotic resistance transcriptional regulator; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.720 |
rclR | chbR | b0305 | b1735 | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | 0.475 |
rclR | marA | b0305 | b1531 | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | Multiple antibiotic resistance transcriptional regulator; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | 0.734 |
rclR | rhaR | b0305 | b3906 | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | Transcriptional activator of rhaSR; Activates expression of the rhaSR operon in response to L- rhamnose. | 0.684 |
rclR | rob | b0305 | b4396 | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | Right oriC-binding transcriptional activator, AraC family; Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication. | 0.676 |
rclR | soxS | b0305 | b4062 | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | Superoxide response regulon transcriptional activator; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters. | 0.741 |
rclR | ydiP | b0305 | b1696 | Reactive chlorine species (RCS)-specific activator of the rcl genes; Involved in reactive chlorine species (RCS) stress resistance. Upregulates, in response to hypochlorous acid (HOCl), the expression of three genes essential for survival of RCS stress (rclA, rclB and rclC) and its own expression. | Putative ARAC-type regulatory protein; Protein involved in transcription and regulation of transcription, DNA-dependent. | 0.800 |