STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheMphenylalanyl-tRNA synthetase (pheST) operon leader peptide; Protein involved in tRNA aminoacylation for protein translation. (14 aa)    
Predicted Functional Partners:
argK
Membrane ATPase/protein kinase; Binds and hydrolyzes GTP. Likely functions as a G-protein chaperone that assists AdoCbl cofactor delivery to the methylmalonyl-CoA mutase (MCM) ScpA and reactivation of the enzyme during catalysis; Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.
      
 0.819
cysQ
3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Has 10000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2); Belongs to the inositol monophosphatase superfamily. CysQ family.
      
 0.785
pheL
Leader peptide of chorismate mutase-P-prephenate dehydratase; Protein involved in L-phenylalanine biosynthetic process.
   
  
 0.649
trpL
Trp operon leader peptide; This protein is involved in control of the biosynthesis of tryptophan.
      
 0.644
hisL
His operon leader peptide; Protein involved in histidine biosynthetic process.
      
 0.622
pheS
Phenylalanine tRNA synthetase, alpha-subunit; Protein involved in tRNA aminoacylation for protein translation.
  
  
 0.587
rplT
50S ribosomal subunit protein L20; One of the primary rRNA binding proteins, it binds close to the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly.
  
  
 0.546
pyrL
pyrBI operon leader peptide; Protein involved in pyrimidine nucleotide biosynthetic process.
      
 0.529
ivbL
ilvB operon leader peptide; This protein is involved in control of the biosynthesis of isoleucine, leucine, and valine.
      
 0.521
thrL
Thr operon leader peptide; This protein is involved in control of the biosynthesis of threonine.
      
 0.520
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.