STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
astBCatalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2) (447 aa)    
Predicted Functional Partners:
astA
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine
 
 
 0.999
astC
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase.
 
 
 0.999
astE
Transforms N(2)-succinylglutamate into succinate and glutamate
 
  
 0.998
astD
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. Also shows activity with decanal or succinic semialdehyde as the electron donor and NAD as the electron acceptor. No activity is detected with NADP as the electron acceptor. Therefore, is an aldehyde dehydrogenase with broad substrate specificity
 
  
 0.998
yigA
annotation not available
      
 0.609
yniA
Ketoamine kinase that phosphorylates ketoamines on the third carbon of the sugar moiety to generate ketoamine 3-phosphate (By similarity). Its precise substrate are unknown: does not have ribulosamine and/or erythrulosamine 3-kinase activity in vitro
   
  
 0.588
putA
Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon
  
  
 0.587
ydiK
annotation not available
   
  
 0.528
tfaE
Prophage tail fiber assembly protein homolog TfaE; Phage or Prophage Related
      
 0.520
cedA
Activates the cell division inhibited by chromosomal DNA over-replication
      
 0.514
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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