STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeaHDUF444 domain-containing protein YeaH; Belongs to the UPF0229 family (427 aa)    
Predicted Functional Partners:
yeaG
Protein kinase, endogenous substrate unidentified; Belongs to the PrkA family
 
  
 0.999
ycgB
Spovr family stationary phase protein; To B.subtilis SpoVR
 
 
 0.997
yegP
DUF1508 domain-containing protein YegP; Belongs to the UPF0339 family. Duplicated subfamily
   
    0.768
ldtE
Murein l,d-transpeptidase; Responsible, at least in part, for generating a meso- diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link
   
    0.760
talA
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
   
    0.759
yiaG
HTH_CROC1 family putative transcriptional regulator; Uncharacterized HTH-type transcriptional regulator YiaG; Protein involved in regulation of transcription, DNA-dependent
   
    0.754
yodD
annotation not available
   
    0.749
fic
Putative adenosine monophosphate--protein transferase fic; Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (By similarity). Involved in cell filamentation induced by cyclic AMP. May have some role in cell division
   
    0.747
ygaM
annotation not available
   
    0.746
patA
putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4- aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal, which allows E.coli to grow on putrescine as the sole nitrogen source . Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cad [...]
   
    0.746
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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