STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsrBUncharacterized protein. (62 aa)    
Predicted Functional Partners:
yffR
CPZ-55 prophage; uncharacterized protein.
   
  
 0.806
ygaC
Uncharacterized protein.
      
 0.804
yciZ
Uncharacterized protein.
      
 0.803
yodD
Uncharacterized protein.
  
  
 0.785
ydcY
DUF2526 family protein.
      
 0.645
yjbT
Putative periplasmic protein; Belongs to the YjbT family.
      
 0.601
yjiM
Putative 2-hydroxyglutaryl-CoA dehydratase; Belongs to the FldB/FldC dehydratase alpha/beta subunit family.
      
 0.599
hycA
Regulator of the transcriptional regulator FhlA; Regulatory protein for the formate hydrogenlyase system. Could act by directly interacting with FhlA or by preventing the binding of FhlA to the upstream activatory sequence. Also down-regulates expression of the hyf operon.
      
 0.522
mcrA
Putative 5-methylcytosine/5-hydroxymethylcytosine-specific restriction nuclease; Restriction of 5-methyl and 5-hydroxymethylcytosines at the specific DNA sequence C(me)CGG.
      
 0.519
ymgI
Uncharacterized protein.
      
 0.477
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.