node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccmA | ccmB | b2201 | b2200 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmA | ccmC | b2201 | b2199 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmA | ccmD | b2201 | b2198 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Cytochrome c biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmA | ccmE | b2201 | b2197 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Periplasmic heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH; Belongs to the CcmE/CycJ family. | 0.998 |
ccmA | ccmF | b2201 | b2196 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.992 |
ccmA | ccmH | b2201 | b2194 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme lyase, CcmH subunit; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.991 |
ccmA | dsbE | b2201 | b2195 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Periplasmic thioredoxin of cytochrome c-type biogenesis; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase. DsbE is maintained in a reduced state by DsbD. | 0.989 |
ccmA | napB | b2201 | b2203 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Nitrate reductase, small, cytochrome C550 subunit, periplasmic; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor; Belongs to the NapB family. | 0.899 |
ccmA | nrfE | b2201 | b4074 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.798 |
ccmA | nrfF | b2201 | b4075 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfF; Not required for the biosynthesis of any of the c-type cytochromes. Possible subunit of a heme lyase. | 0.867 |
ccmB | ccmA | b2200 | b2201 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | 0.999 |
ccmB | ccmC | b2200 | b2199 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmB | ccmD | b2200 | b2198 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Cytochrome c biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmB | ccmE | b2200 | b2197 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Periplasmic heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH; Belongs to the CcmE/CycJ family. | 0.999 |
ccmB | ccmF | b2200 | b2196 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.993 |
ccmB | ccmH | b2200 | b2194 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme lyase, CcmH subunit; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.966 |
ccmB | dsbE | b2200 | b2195 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Periplasmic thioredoxin of cytochrome c-type biogenesis; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase. DsbE is maintained in a reduced state by DsbD. | 0.985 |
ccmB | napB | b2200 | b2203 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Nitrate reductase, small, cytochrome C550 subunit, periplasmic; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor; Belongs to the NapB family. | 0.868 |
ccmB | nrfE | b2200 | b4074 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.821 |
ccmB | nrfF | b2200 | b4075 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfF; Not required for the biosynthesis of any of the c-type cytochromes. Possible subunit of a heme lyase. | 0.840 |