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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfdEAcetyl-coa:oxalate coa-transferase; Involved in the catabolism of oxalate and in the adapatation to low pH. ACOCT serves to prime the oxalate-induced acid tolerance response (ATR) cycle by producing substrate for oxalyl-CoA decarboxylase (OXC) and formyl-coenzyme A transferase (FCOCT). Catalyzes the reversible conversion of acetyl-CoA and oxalate to oxalyl-CoA and acetate. It can also use formyl-CoA and oxalate to produce oxalyl-CoA and formate with significantly reduced specific activity (381 aa)    
Predicted Functional Partners:
yfdV
Malonate transporter and related proteins; Uncharacterized transporter YfdV; Putative receptor protein
  
 0.992
oxc
Oxalyl coa decarboxylase, thdp-dependent; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the decarboxylation of oxalyl-CoA to yield carbon dioxide and formyl-CoA
 
 0.980
yfdX
annotation not available
  
  
 0.901
yhiJ
annotation not available
      
 0.739
frc
Formyl-coa transferase, nad(p)-binding; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate. It can also use succinate as an acceptor
 
  
0.655
yejA
Putative oligopeptide abc transporter periplasmic binding protein; To H.influenzae HbpA
      
 0.641
paaH
3-hydroxyadipyl-CoA dehydrogenase, NAD+-dependent; Catalyzes the oxidation of 3-hydroxyadipyl-CoA to yield 3- oxoadipyl-CoA
 
  
 0.604
ydeN
Putative ser-type periplasmic non-aryl sulfatase; Belongs to the sulfatase family
  
   
 0.574
yphC
Putative zn-dependent nad(p)-binding oxidoreductase; Uncharacterized zinc-type alcohol dehydrogenase-like protein YphC; Putative oxidoreductase
   
  
 0.527
chbB
N,n'-diacetylchitobiose-specific enzyme iib component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2) . Also able to use N,N',N''-triacetyl chitotriose (GlcNAc3)
      
 0.511
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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