STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfhLPutative 4fe-4s cluster-containing protein yfhl; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions (86 aa)    
Predicted Functional Partners:
pfo
Pyruvate-ferredoxin/flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
  
  
 0.770
yjaH
annotation not available
      
 0.733
ybbJ
annotation not available
      
 0.731
shoB
Small toxic protein shob; Toxic component of a type I toxin-antitoxin (TA) system. May be a toxic protein; overexpression causes cessation of growth and rapid membrane depolarization. Overexpression induces stress-response and a number of membrane protein genes
      
 0.731
yadE
Putative polysaccharide deacetylase lipoprotein; Uncharacterized protein YadE
      
 0.703
acpS
Holo-[acyl-carrier-protein] synthase 1; Transfers the 4'-phosphopantetheine moiety from coenzyme A to the 'Ser-36' of acyl-carrier-protein
      
 0.679
yjjV
Tatd dnase family protein; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family
  
  
 0.665
yfhH
annotation not available
       0.663
ybjT
Putative NAD(P)-binding protein YbjT; Putative enzyme; Not classified
      
 0.613
yafL
Putative lipoprotein and c40 family peptidase; Probable endopeptidase YafL; Putative lipoprotein
      
 0.606
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.