STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ypjAAdhesin-like autotransporter; Putative ATP-binding component of a transport system. (1526 aa)    
Predicted Functional Partners:
evgS
Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals.
  
   
 0.786
hdeD
Acid-resistance membrane protein.
  
     0.690
yegI
Protein kinase-related putative non-specific DNA-binding protein; Probable serine/threonine kinase.
  
    0.674
ycbF
Putative periplasmic pilin chaperone; Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of fimbriae; Belongs to the periplasmic pilus chaperone family.
  
    0.635
rhsA
Rhs protein with putative toxin 55 domain; Rhs elements have a nonessential function. They may play an important role in the natural ecology of the cell; Belongs to the RHS family.
  
    0.624
fhuA
Ferrichrome outer membrane transporter; Involved in the uptake of iron in complex with ferrichrome, a hydroxamate-type siderophore. Binds and transports ferrichrome-iron across the outer membrane. In addition to its role in ferrichrome-iron transport, transports the antibiotic albomycin, which is a structural analog of ferrichrome, and acts as a receptor for colicin M, microcin J25 and bacteriophages T1, T5, phi80 and UC-1. The energy source, which is required for all FhuA functions except infection by phage T5, is provided by the inner membrane TonB system.
  
 
 
 0.623
rhsB
Rhs protein with DUF4329 family putative toxin domain; Rhs elements have a nonessential function. They may play an important role in the natural ecology of the cell; Belongs to the RHS family.
  
    0.622
rhsC
Rhs protein with putative toxin domain; Rhs elements have a nonessential function. They may play an important role in the natural ecology of the cell.
  
    0.621
yghD
Putative membrane-anchored secretion pathway M-type protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane.
  
     0.619
yhbX
Putative EptAB family phosphoethanolamine transferase, inner membrane protein; Probably does not transfer phosphoethanolamine to lipid A. Belongs to the phosphoethanolamine transferase family.
  
     0.619
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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