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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proWGlycine betaine/proline transport system permease protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake Probably responsible for the translocation of the substrate across the membrane (Probable) (354 aa)    
Predicted Functional Partners:
proV
Glycine betaine/proline abc transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake Probably responsible for energy coupling to the transport system (Probable)
 0.999
proX
Glycine betaine/proline abc transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity
 
 0.999
osmF
Glycine betaine abc transporter periplasmic binding protein osmf; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Binds glycine betaine with low affinity
 
 
 0.908
malF
Maltose/maltodextrin transport system permease protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane
     
 0.793
ugpE
Sn-glycerol 3-phosphate abc transporter membrane subunit ugpe; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane
     
 0.790
ugpA
Sn-glycerol 3-phosphate abc transporter membrane subunit ugpa; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane
     
 0.788
cydD
Glutathione/cysteine abc transporter export permease/atpase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system
     
 0.780
ugpC
Sn-glycerol 3-phosphate transport system atp-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters
 
   
 0.780
kdpA
Potassium-transporting atpase potassium-binding subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm This subunit binds and transports the potassium across the cytoplasmic membrane
     
 0.775
metN
L-methionine/d-methionine abc transporter atp binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import Responsible for energy coupling to the transport system . It has also been shown to be involved in formyl-L-methionine transport
 
  
  0.766
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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