node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dsbC | fldB | b2893 | b2895 | Protein disulfide isomerase II; Acts as a disulfide isomerase, interacting with incorrectly folded proteins to correct non-native disulfide bonds. DsbG and DsbC are part of a periplasmic reducing system that controls the level of cysteine sulfenylation, and provides reducing equivalents to rescue oxidatively damaged secreted proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by DsbD. | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | 0.576 |
dsbC | lysS | b2893 | b2890 | Protein disulfide isomerase II; Acts as a disulfide isomerase, interacting with incorrectly folded proteins to correct non-native disulfide bonds. DsbG and DsbC are part of a periplasmic reducing system that controls the level of cysteine sulfenylation, and provides reducing equivalents to rescue oxidatively damaged secreted proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by DsbD. | Lysine tRNA synthetase, constitutive; suppressor of ColE1 mutation in primer RNA; Protein involved in tRNA aminoacylation for protein translation; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.567 |
dsbC | recJ | b2893 | b2892 | Protein disulfide isomerase II; Acts as a disulfide isomerase, interacting with incorrectly folded proteins to correct non-native disulfide bonds. DsbG and DsbC are part of a periplasmic reducing system that controls the level of cysteine sulfenylation, and provides reducing equivalents to rescue oxidatively damaged secreted proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by DsbD. | ssDNA exonuclease, 5' --> 3'-specific; Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available. | 0.821 |
dsbC | xerD | b2893 | b2894 | Protein disulfide isomerase II; Acts as a disulfide isomerase, interacting with incorrectly folded proteins to correct non-native disulfide bonds. DsbG and DsbC are part of a periplasmic reducing system that controls the level of cysteine sulfenylation, and provides reducing equivalents to rescue oxidatively damaged secreted proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by DsbD. | Site-specific tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids at ColE1 xer (or cer) and pSC101 (or [...] | 0.831 |
entB | fldB | b0595 | b2895 | Isochorismatase; Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3- dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP). Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), the precursor of 2,3- dihydroxybenzoate (DHB). In the enterob [...] | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | 0.570 |
entB | mioC | b0595 | b3742 | Isochorismatase; Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3- dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP). Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), the precursor of 2,3- dihydroxybenzoate (DHB). In the enterob [...] | FMN-binding protein MioC; Probable electron transporter required for biotin synthase activity. | 0.570 |
entB | yqcA | b0595 | b2790 | Isochorismatase; Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3- dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP). Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), the precursor of 2,3- dihydroxybenzoate (DHB). In the enterob [...] | Short-chain flavodoxin, FMN-binding; Probable electron transporter; Belongs to the flavodoxin family. MioC subfamily. | 0.570 |
fldB | dsbC | b2895 | b2893 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Protein disulfide isomerase II; Acts as a disulfide isomerase, interacting with incorrectly folded proteins to correct non-native disulfide bonds. DsbG and DsbC are part of a periplasmic reducing system that controls the level of cysteine sulfenylation, and provides reducing equivalents to rescue oxidatively damaged secreted proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by DsbD. | 0.576 |
fldB | entB | b2895 | b0595 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Isochorismatase; Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3- dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP). Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), the precursor of 2,3- dihydroxybenzoate (DHB). In the enterob [...] | 0.570 |
fldB | fpr | b2895 | b3924 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | ferredoxin-NADP reductase; Transports electrons between flavodoxin or ferredoxin and NADPH. Reduces flavodoxin 1, flavodoxin 2 and ferredoxin, ferredoxin being the kinetically and thermodynamically preferred partner. Required for the activation of several enzymes such as pyruvate formate-lyase, anaerobic ribonucleotide reductase and cobalamin-dependent methionine synthase. Belongs to the ferredoxin--NADP reductase type 1 family. | 0.598 |
fldB | lysS | b2895 | b2890 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Lysine tRNA synthetase, constitutive; suppressor of ColE1 mutation in primer RNA; Protein involved in tRNA aminoacylation for protein translation; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.491 |
fldB | mioC | b2895 | b3742 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | FMN-binding protein MioC; Probable electron transporter required for biotin synthase activity. | 0.531 |
fldB | pfo | b2895 | b1378 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.635 |
fldB | recJ | b2895 | b2892 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | ssDNA exonuclease, 5' --> 3'-specific; Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available. | 0.565 |
fldB | xerD | b2895 | b2894 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Site-specific tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids at ColE1 xer (or cer) and pSC101 (or [...] | 0.594 |
fldB | yfaE | b2895 | b2236 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Uncharacterized ferredoxin-like protein YfaE; Ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance. | 0.439 |
fldB | yqcA | b2895 | b2790 | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Short-chain flavodoxin, FMN-binding; Probable electron transporter; Belongs to the flavodoxin family. MioC subfamily. | 0.502 |
fpr | fldB | b3924 | b2895 | ferredoxin-NADP reductase; Transports electrons between flavodoxin or ferredoxin and NADPH. Reduces flavodoxin 1, flavodoxin 2 and ferredoxin, ferredoxin being the kinetically and thermodynamically preferred partner. Required for the activation of several enzymes such as pyruvate formate-lyase, anaerobic ribonucleotide reductase and cobalamin-dependent methionine synthase. Belongs to the ferredoxin--NADP reductase type 1 family. | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | 0.598 |
fpr | yfaE | b3924 | b2236 | ferredoxin-NADP reductase; Transports electrons between flavodoxin or ferredoxin and NADPH. Reduces flavodoxin 1, flavodoxin 2 and ferredoxin, ferredoxin being the kinetically and thermodynamically preferred partner. Required for the activation of several enzymes such as pyruvate formate-lyase, anaerobic ribonucleotide reductase and cobalamin-dependent methionine synthase. Belongs to the ferredoxin--NADP reductase type 1 family. | Uncharacterized ferredoxin-like protein YfaE; Ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance. | 0.789 |
lysS | dsbC | b2890 | b2893 | Lysine tRNA synthetase, constitutive; suppressor of ColE1 mutation in primer RNA; Protein involved in tRNA aminoacylation for protein translation; Belongs to the class-II aminoacyl-tRNA synthetase family. | Protein disulfide isomerase II; Acts as a disulfide isomerase, interacting with incorrectly folded proteins to correct non-native disulfide bonds. DsbG and DsbC are part of a periplasmic reducing system that controls the level of cysteine sulfenylation, and provides reducing equivalents to rescue oxidatively damaged secreted proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by DsbD. | 0.567 |