STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pppALeader peptidase PppA; Putative enzyme; Not classified (269 aa)    
Predicted Functional Partners:
yghG
Uncharacterized lipoprotein YghG; Pseudogene, secretion pathway protein, C-type protein homology;putative transport; Not classified; putative general secretion pathway for protein export (GSP)
  
 
 0.981
sslE
Putative lipoprotein
 
  
 0.981
gspC
Putative type II secretion system protein C; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
     
 0.930
hofC
Protein transport protein HofC homolog; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake
 
  
 0.882
yggR
Uncharacterized protein YggR; Putative protein transport
 
  
 0.866
gspE
Putative type II secretion system protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
 
  
 0.834
hofB
Protein transport protein HofB homolog; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake; Belongs to the GSP E family
 
  
 0.830
gspF
Putative type II secretion system protein F; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
 
  
 0.823
gspG
Putative type II secretion system protein G; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
 
  
 0.754
hofQ
DNA utilization protein HofQ; Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane
 
  
 0.702
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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