STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhaKRedox-sensitive bicupin; Does not have quercetin 2,3-dioxygenase activity. Belongs to the pirin family. (233 aa)    
Predicted Functional Partners:
yhaJ
LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity).
 
 
 
 0.964
ybiJ
DUF1471 family putative periplasmic protein.
   
  
 0.879
yqjF
Putative quinol oxidase subunit.
  
  
 0.831
yedP
Putative mannosyl-3-phosphoglycerate phosphatase.
      
 0.815
ygiD
4,5- DOPA-extradiol-dioxygenase; In vitro, opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown.
 
  
 0.791
yhcN
Cadmium and peroxide resistance protein, stress-induced.
   
  
 0.785
yhaL
Uncharacterized protein.
       0.701
azoR
NADH-azoreductase, FMN-dependent; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity. The enzyme can reduce ethyl red and methyl red, but is not able to convert sulfonated azo dyes; Belongs to the azoreductase type 1 family.
  
  
 0.530
yhaO
Putative transporter; Plays a role in L-cysteine detoxification. May transport both D- and L-serine (By similarity). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
      
 0.523
thiB
Thiamine/thiamine pyrophosphate/thiamine monophosphate ABC transporter periplasmic binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Binds thiamine, thiamine phosphate and thiamine diphosphate with high affinity ; Belongs to the bacterial solute-binding protein 1 family.
      
 0.518
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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