node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gspA | gspB | b3323 | b3322 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | 0.992 |
gspA | gspC | b3323 | b3324 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.956 |
gspA | gspE | b3323 | b3326 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.761 |
gspA | gspF | b3323 | b3327 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.755 |
gspA | gspG | b3323 | b3328 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | Pseudopilin, cryptic, general secretion pathway; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.714 |
gspA | gspL | b3323 | b3333 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.845 |
gspA | gspM | b3323 | b3334 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.749 |
gspA | gspO | b3323 | b3335 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.847 |
gspA | gss | b3323 | b2988 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | Glutathionylspermidine amidase and glutathionylspermidine synthetase; Catalyzes the formation of an amide bond between glutathione (GSH) and spermidine coupled with hydrolysis of ATP; also catalyzes the opposing reaction, i.e. the hydrolysis of glutathionylspermidine (Gsp) back to glutathione and spermidine. The amidase active site can also hydrolyze Gsp-disulfide (Gsp-S-S-Gsp) to Gsp-SG and Gsp S-thiolated proteins (GspSSPs) to GSH S-thiolated protein (GSSPs). Likely acts synergistically with glutaredoxin to regulate the redox environment of E.coli and defend against oxidative damage. [...] | 0.809 |
gspA | yacC | b3323 | b0122 | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | PulS_OutS family protein. | 0.845 |
gspB | gspA | b3322 | b3323 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | 0.992 |
gspB | gspC | b3322 | b3324 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.820 |
gspB | gspE | b3322 | b3326 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.681 |
gspB | gspF | b3322 | b3327 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.631 |
gspB | gspG | b3322 | b3328 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | Pseudopilin, cryptic, general secretion pathway; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.533 |
gspB | gspL | b3322 | b3333 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.610 |
gspB | gspM | b3322 | b3334 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | 0.600 |
gspB | gspO | b3322 | b3335 | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | Bifunctional prepilin leader peptidase/ methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.546 |
gspC | gspA | b3324 | b3323 | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | General secretory pathway component, cryptic; May play a regulatory role under conditions of derepressed gsp gene expression; Belongs to the ExeA family. | 0.956 |
gspC | gspB | b3324 | b3322 | General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. | Part of gsp divergon involved in type II protein secretion; Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions. May play a regulatory role under conditions of derepressed gsp gene expression. | 0.820 |