STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yidBannotation not available (132 aa)    
Predicted Functional Partners:
mdtO
Multidrug resistance protein MdtO; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
  
     0.595
ivy
Inhibitor of vertebrate lysozyme; Strong inhibitor of lysozyme C
  
     0.575
yidA
Sugar phosphatase YidA; Catalyzes the dephosphorylation of different sugar phosphates including erythrose-4-phosphate (Ery4P), ribose-5- phosphate (Ribu5P), fructose-1-phosphate (Fru1P), fructose-6- phosphate (Fru6P), glucose-6-P (Glu6P), and also imidodiphosphate (Imido-di-P) and acetyl phosphate (Acetyl-P). Selectively hydrolyzes alpha-D-glucose-1-phosphate (Glu1P) and has no activity with the beta form
       0.553
yebB
annotation not available
  
     0.510
ydhQ
Uncharacterized protein YdhQ; Possible enzyme
  
     0.507
ybcH
annotation not available
  
     0.494
nfrA
Bacteriophage adsorption protein A; (Microbial infection) Allows N4 phage attachment by binding to the viral non-contractile sheath protein
  
 
   0.484
mdtP
Multidrug resistance outer membrane protein MdtP; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
  
     0.463
yfbM
annotation not available
  
     0.452
gyrB
DNA gyrase subunit B; DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner to maintain chromosomes in an underwound state. This makes better substrates for topoisomerase 4 (ParC and ParE) which is the main enzyme that unlinks newly replicated chromosomes in E.coli. Gyrase catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes. Relaxes negatively supercoiled DNA in an ATP-independent manner. E.coli gyrase has higher supercoiling activity than other characterized bacterial gyrases; at compar [...]
       0.444
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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