STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
yihV6-deoxy-6-sulphofructose kinase; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP); Belongs to the carbohydrate kinase PfkB family. (298 aa)    
Predicted Functional Partners:
yihT
6-deoxy-6-sulphofructose-1-phosphate aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family.
 
 
 0.988
yihS
Sulphoquinovose isomerase; Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF). In vitro, can also catalyze the interconversion of mannose, fructose and glucose, or lyxose and xylulose, but has extremely low activity with glucose.
  
 
 0.971
yihW
Putative transcriptional regulator for sulphoquinovose utilization; Involved in the regulation of the sulfoquinovose operon. Represses the expression of the yihUTS operon and of the yihV and csqR genes. Binds DNA inside the spacer between the bidirectional transcription units comprising the yihUTS operon and the yihV gene, and upstream the csqR gene itself.
  
  
 0.967
yihU
3-sulpholactaldehyde (SLA) reductase, NADH-dependent; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS).
  
  
 0.956
yihQ
Putative sulpholipid alpha-glucosidase; Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E.coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur. Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids. Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro). Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ. Also exhibits some alpha-glucosid [...]
 
  
 0.919
yihR
Putative sulphoquinovose mutarotase; Putative aldose-1-epimerase.
  
  
 0.877
yihP
Putative 2,3-dihydroxypropane-1-sulphonate exporter, membrane protein; Could be involved in the export of 2,3-dihydroxypropane-1- sulfonate (DHPS); Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
     
 0.842
yihO
Putative sulphoquinovose importer; Could be involved in sulfoquinovose import.
  
  
 0.840
rbsD
D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta- allofuranose and beta-allopyranose; Belongs to the RbsD / FucU family. RbsD subfamily.
 
  
 0.771
ydcV
Putative ABC transporter permease; Involved in natural transformation. Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane. During natural transformation, may serve as the channel for dsDNA uptake (Probable).
      
 0.731
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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