STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yihV6-deoxy-6-sulphofructose kinase; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP) (298 aa)    
Predicted Functional Partners:
yihS
Sulfoquinovose isomerase; Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF). In vitro, can also catalyze the interconversion of mannose, fructose and glucose, or lyxose and xylulose, but has extremely low activity with glucose
 
  
 0.996
yihT
6-deoxy-6-sulphofructose-1-phosphate aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA)
 
 
 0.996
yihW
Putative transcriptional regulator for sulphoquinovose utilization; Involved in the regulation of the sulfoquinovose operon . Represses the expression of the yihUTS operon and of the yihV and csqR genes. Binds DNA inside the spacer between the bidirectional transcription units comprising the yihUTS operon and the yihV gene, and upstream the csqR gene itself
 
  
 0.980
yihU
4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS)
 
  
 0.969
yihR
Putative sulphoquinovose mutarotase; Uncharacterized protein YihR; Putative aldose-1-epimerase
 
  
 0.939
yihQ
Putative sulpholipid alpha-glucosidase; Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E.coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur. Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids. Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro). Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ . Also exhibits some alpha-glucosi [...]
 
   
 0.928
yihO
Glycoside/pentoside/hexuronide:cation symporter, gph family; Could be involved in sulfoquinovose import
 
  
 0.924
ompL
Oligogalacturonate-specific porin family protein; Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown
 
   
 0.771
yfdC
Formate-nitrite transporter family protein; Inner membrane protein YfdC; Putative transport protein
      
 0.641
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate
   
  
 0.624
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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