node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
exuR | exuT | b3094 | b3093 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Hexuronate transporter; Aldohexuronate transport system. | 0.976 |
exuR | uxaA | b3094 | b3091 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Altronate hydrolase; Catalyzes the dehydration of D-altronate. | 0.846 |
exuR | uxaC | b3094 | b3092 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Uronate isomerase; Protein involved in carbohydrate catabolic process; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. | 0.824 |
exuR | uxuA | b3094 | b4322 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Mannonate hydrolase; Catalyzes the dehydration of D-mannonate. | 0.822 |
exuR | uxuB | b3094 | b4323 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | D-mannonate oxidoreductase, NAD-dependent; D-mannonate oxidoreductase; Protein involved in carbohydrate catabolic process; Belongs to the mannitol dehydrogenase family. UxuB subfamily. | 0.808 |
exuR | uxuR | b3094 | b4324 | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | 0.421 |
exuT | exuR | b3093 | b3094 | Hexuronate transporter; Aldohexuronate transport system. | Hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. | 0.976 |
exuT | uxaA | b3093 | b3091 | Hexuronate transporter; Aldohexuronate transport system. | Altronate hydrolase; Catalyzes the dehydration of D-altronate. | 0.920 |
exuT | uxaC | b3093 | b3092 | Hexuronate transporter; Aldohexuronate transport system. | Uronate isomerase; Protein involved in carbohydrate catabolic process; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. | 0.928 |
exuT | uxuA | b3093 | b4322 | Hexuronate transporter; Aldohexuronate transport system. | Mannonate hydrolase; Catalyzes the dehydration of D-mannonate. | 0.826 |
exuT | uxuB | b3093 | b4323 | Hexuronate transporter; Aldohexuronate transport system. | D-mannonate oxidoreductase, NAD-dependent; D-mannonate oxidoreductase; Protein involved in carbohydrate catabolic process; Belongs to the mannitol dehydrogenase family. UxuB subfamily. | 0.810 |
exuT | uxuR | b3093 | b4324 | Hexuronate transporter; Aldohexuronate transport system. | Fructuronate-inducible hexuronate regulon transcriptional repressor; Repressor for the uxuRBA operon. | 0.857 |
kdgK | rspA | b3526 | b1581 | 2-dehydro-3-deoxygluconokinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family. | Bifunctional D-altronate/D-mannonate dehydratase; Probably involved in the degradation of homoserine lactone (HSL) or of a metabolite of HSL that signals starvation. | 0.887 |
kdgK | uxaA | b3526 | b3091 | 2-dehydro-3-deoxygluconokinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family. | Altronate hydrolase; Catalyzes the dehydration of D-altronate. | 0.979 |
kdgK | uxaC | b3526 | b3092 | 2-dehydro-3-deoxygluconokinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family. | Uronate isomerase; Protein involved in carbohydrate catabolic process; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. | 0.930 |
kdgK | uxuA | b3526 | b4322 | 2-dehydro-3-deoxygluconokinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family. | Mannonate hydrolase; Catalyzes the dehydration of D-mannonate. | 0.986 |
kdgK | uxuB | b3526 | b4323 | 2-dehydro-3-deoxygluconokinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family. | D-mannonate oxidoreductase, NAD-dependent; D-mannonate oxidoreductase; Protein involved in carbohydrate catabolic process; Belongs to the mannitol dehydrogenase family. UxuB subfamily. | 0.913 |
mtlA | uxuB | b3599 | b4323 | Mannitol-specific PTS enzyme: IIA, IIB and IIC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in D-mannitol transport. Also able to use D-mannonic acid. | D-mannonate oxidoreductase, NAD-dependent; D-mannonate oxidoreductase; Protein involved in carbohydrate catabolic process; Belongs to the mannitol dehydrogenase family. UxuB subfamily. | 0.922 |
rspA | kdgK | b1581 | b3526 | Bifunctional D-altronate/D-mannonate dehydratase; Probably involved in the degradation of homoserine lactone (HSL) or of a metabolite of HSL that signals starvation. | 2-dehydro-3-deoxygluconokinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family. | 0.887 |
rspA | rspB | b1581 | b1580 | Bifunctional D-altronate/D-mannonate dehydratase; Probably involved in the degradation of homoserine lactone (HSL) or of a metabolite of HSL that signals starvation. | Starvation-sensing protein RspB; Not known; probable catabolic enzyme. | 0.989 |