STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhaMPutative L-serine dehydratase alpha chain; Plays a role in L-cysteine detoxification; it has been speculated to be a cysteine desulfhydrase. (436 aa)    
Predicted Functional Partners:
yhaO
Putative transporter; Plays a role in L-cysteine detoxification. May transport both D- and L-serine (By similarity). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
 
  
 0.992
ybaO
Putative DNA-binding transcriptional regulator; Plays a role in L-cysteine detoxification. Binds to the dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L- cysteine; activates transcription from the dlsT(yhaO)-yhaM operon. No other DNA target was identified in strain K12 / BW25113. Thiosulfate does not activate its transcription function. Overexpression doubles hydrogen sulfide production in the presence of cysteine.
      
 0.624
yjjI
DUF3029 family protein, putative glycine radical enzyme.
  
   
 0.580
ydaU
Rac prophage; conserved protein.
      
 0.503
yeiI
Putative kinase; Belongs to the carbohydrate kinase PfkB family.
      
 0.457
psuT
Putative nucleoside transporter; Could be involved in pseudouridine transport; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
   
  
 0.455
tdcG
L-serine dehydratase; Protein involved in cellular amino acid catabolic process.
  
    0.437
ygbA
Uncharacterized protein.
  
  
 0.425
ytfL
UPF0053 family inner membrane protein; Putative transport protein.
      
 0.402
yhfK
Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process.
      
 0.400
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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