STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yghGLipoprotein YghG; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane. In a functional T2SS this subunit helps assemble the outer membrane channel; Belongs to the GspS/AspS pilotin family. (136 aa)    
Predicted Functional Partners:
pppA
Bifunctional prepilin leader peptidase/ methylase; A pre-pilin peptidase involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane.
  
  
 0.973
sslE
Putative secreted and surface-associated lipoprotein mucinase; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane.
  
  
 0.964
gspD
General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane. This subunit would form the outer membrane channel.
   
 
 0.825
yacC
PulS_OutS family protein.
      
 0.809
ybfP
Lipoprotein; Putative pectinase.
   
  
 0.762
yqhG
DUF3828 family putative periplasmic protein.
      
 0.624
pqiC
DUF330 family putative lipoprotein; Component of a transport pathway that contributes to membrane integrity.
      
 0.621
yeaY
Slp family lipoprotein, RpoE-regulated; Putative outer membrane protein.
      
 0.560
yfbO
Uncharacterized protein.
      
 0.543
ecnB
Entericidin B membrane lipoprotein; Plays a role in the bacteriolysis. Is activated under conditions of high osmolarity by the factor sigma S. Entericidin A functions as an antidote; Belongs to the EcnA/EcnB lipoprotein family.
      
 0.543
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.