Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAK1P21 (RAC1) activated kinase 1. (544 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.994
PAK2
P21 (RAC1) activated kinase 2.
   
  0.989
NCK2
NCK adaptor protein 2.
    
 0.986
NCK1
NCK adaptor protein 1.
    
 0.986
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.984
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.984
RAC1
Rac family small GTPase 1.
    
 0.978
RAC3
Rac family small GTPase 3.
    
 0.976
RAC2
Rac family small GTPase 2.
    
 0.973
GIT1
GIT ArfGAP 1.
    
 0.968
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.