EDA protein (Catagonus wagneri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

EDA

Ectodysplasin A. (259 aa)

Predicted Functional Partners:

EDAR

0.922

LIG1

0.909

ENSCWAP00000001138

0.898

MAP3K7

0.840

MAP3K20

0.840

MAP2K7

0.830

MAPK10

0.827

MAPK8

0.827

MAPK9

0.827

DUSP16

0.790

Your Current Organism:

Catagonus wagneri

NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP16	EDA	ENSCWAP00000015758	ENSCWAP00000001113	Dual specificity phosphatase 16.	Ectodysplasin A.	0.790
DUSP16	ENSCWAP00000001138	ENSCWAP00000015758	ENSCWAP00000001138	Dual specificity phosphatase 16.	annotation not available	0.790
DUSP16	MAP2K7	ENSCWAP00000015758	ENSCWAP00000019838	Dual specificity phosphatase 16.	Mitogen-activated protein kinase kinase 7.	0.865
DUSP16	MAPK10	ENSCWAP00000015758	ENSCWAP00000012005	Dual specificity phosphatase 16.	Mitogen-activated protein kinase 10.	0.988
DUSP16	MAPK8	ENSCWAP00000015758	ENSCWAP00000029275	Dual specificity phosphatase 16.	Mitogen-activated protein kinase 8.	0.955
DUSP16	MAPK9	ENSCWAP00000015758	ENSCWAP00000029343	Dual specificity phosphatase 16.	Mitogen-activated protein kinase 9.	0.986
EDA	DUSP16	ENSCWAP00000001113	ENSCWAP00000015758	Ectodysplasin A.	Dual specificity phosphatase 16.	0.790
EDA	EDAR	ENSCWAP00000001113	ENSCWAP00000006059	Ectodysplasin A.	Ectodysplasin A receptor.	0.922
EDA	ENSCWAP00000001138	ENSCWAP00000001113	ENSCWAP00000001138	Ectodysplasin A.	annotation not available	0.898
EDA	LIG1	ENSCWAP00000001113	ENSCWAP00000018935	Ectodysplasin A.	DNA ligase 1.	0.909
EDA	MAP2K7	ENSCWAP00000001113	ENSCWAP00000019838	Ectodysplasin A.	Mitogen-activated protein kinase kinase 7.	0.830
EDA	MAP3K20	ENSCWAP00000001113	ENSCWAP00000018724	Ectodysplasin A.	Mitogen-activated protein kinase kinase kinase 20.	0.840
EDA	MAP3K7	ENSCWAP00000001113	ENSCWAP00000018552	Ectodysplasin A.	Mitogen-activated protein kinase kinase kinase 7.	0.840
EDA	MAPK10	ENSCWAP00000001113	ENSCWAP00000012005	Ectodysplasin A.	Mitogen-activated protein kinase 10.	0.827
EDA	MAPK8	ENSCWAP00000001113	ENSCWAP00000029275	Ectodysplasin A.	Mitogen-activated protein kinase 8.	0.827
EDA	MAPK9	ENSCWAP00000001113	ENSCWAP00000029343	Ectodysplasin A.	Mitogen-activated protein kinase 9.	0.827
EDAR	EDA	ENSCWAP00000006059	ENSCWAP00000001113	Ectodysplasin A receptor.	Ectodysplasin A.	0.922
EDAR	ENSCWAP00000001138	ENSCWAP00000006059	ENSCWAP00000001138	Ectodysplasin A receptor.	annotation not available	0.943
ENSCWAP00000001138	DUSP16	ENSCWAP00000001138	ENSCWAP00000015758	annotation not available	Dual specificity phosphatase 16.	0.790
ENSCWAP00000001138	EDA	ENSCWAP00000001138	ENSCWAP00000001113	annotation not available	Ectodysplasin A.	0.898