STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC1SHC adaptor protein 1. (584 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.994
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.992
EGFR
Epidermal growth factor receptor.
    
 0.990
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.989
GAB1
GRB2 associated binding protein 1.
    
 0.987
IGF1R
Insulin like growth factor 1 receptor.
    
 0.987
INSR
Insulin receptor.
    
 0.987
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.985
LYN
LYN proto-oncogene, Src family tyrosine kinase.
    
 0.984
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
    
 0.984
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.