NPM1 protein (Catagonus wagneri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

NPM1

Nucleophosmin 1. (294 aa)

Predicted Functional Partners:

NCL

0.997

ENSCWAP00000013956

0.997

RPL4

0.996

RPL23A

0.993

RPL19

0.992

RPL3

0.992

RPL14

0.990

EIF2AK2

0.989

RPL8

0.987

TP53

0.984

Your Current Organism:

Catagonus wagneri

NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK2	NPM1	ENSCWAP00000017767	ENSCWAP00000001295	Eukaryotic translation initiation factor 2 alpha kinase 2.	Nucleophosmin 1.	0.989
EIF2AK2	TP53	ENSCWAP00000017767	ENSCWAP00000005800	Eukaryotic translation initiation factor 2 alpha kinase 2.	Tumor protein p53.	0.989
ENSCWAP00000013956	NCL	ENSCWAP00000013956	ENSCWAP00000005318	annotation not available	Nucleolin.	0.932
ENSCWAP00000013956	NPM1	ENSCWAP00000013956	ENSCWAP00000001295	annotation not available	Nucleophosmin 1.	0.997
ENSCWAP00000013956	RPL14	ENSCWAP00000013956	ENSCWAP00000017401	annotation not available	Ribosomal protein L14.	0.999
ENSCWAP00000013956	RPL19	ENSCWAP00000013956	ENSCWAP00000001971	annotation not available	Ribosomal protein L19.	0.999
ENSCWAP00000013956	RPL23A	ENSCWAP00000013956	ENSCWAP00000007341	annotation not available	Ribosomal protein L23a.	0.999
ENSCWAP00000013956	RPL3	ENSCWAP00000013956	ENSCWAP00000020070	annotation not available	Ribosomal protein L3.	0.999
ENSCWAP00000013956	RPL4	ENSCWAP00000013956	ENSCWAP00000020138	annotation not available	Ribosomal protein L4.	0.999
ENSCWAP00000013956	RPL8	ENSCWAP00000013956	ENSCWAP00000001364	annotation not available	Ribosomal protein L8.	0.999
ENSCWAP00000013956	TP53	ENSCWAP00000013956	ENSCWAP00000005800	annotation not available	Tumor protein p53.	0.973
NCL	ENSCWAP00000013956	ENSCWAP00000005318	ENSCWAP00000013956	Nucleolin.	annotation not available	0.932
NCL	NPM1	ENSCWAP00000005318	ENSCWAP00000001295	Nucleolin.	Nucleophosmin 1.	0.997
NCL	RPL14	ENSCWAP00000005318	ENSCWAP00000017401	Nucleolin.	Ribosomal protein L14.	0.799
NCL	RPL19	ENSCWAP00000005318	ENSCWAP00000001971	Nucleolin.	Ribosomal protein L19.	0.761
NCL	RPL23A	ENSCWAP00000005318	ENSCWAP00000007341	Nucleolin.	Ribosomal protein L23a.	0.782
NCL	RPL3	ENSCWAP00000005318	ENSCWAP00000020070	Nucleolin.	Ribosomal protein L3.	0.978
NCL	RPL4	ENSCWAP00000005318	ENSCWAP00000020138	Nucleolin.	Ribosomal protein L4.	0.953
NCL	RPL8	ENSCWAP00000005318	ENSCWAP00000001364	Nucleolin.	Ribosomal protein L8.	0.928
NCL	TP53	ENSCWAP00000005318	ENSCWAP00000005800	Nucleolin.	Tumor protein p53.	0.956