Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF16Rho guanine nucleotide exchange factor 16. (699 aa)    
Predicted Functional Partners:
MAGI2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
    
   0.910
ENSCWAP00000016037
annotation not available
     
 0.864
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
     
 0.768
CDC42
Cell division cycle 42.
    
 0.758
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
      
 0.754
FMNL3
Formin like 3.
      
 0.754
AKAP13
A-kinase anchoring protein 13.
    
 0.753
ARHGEF7
Rho guanine nucleotide exchange factor 7.
     
 0.736
EPHA2
EPH receptor A2.
    
 0.721
KALRN
Kalirin RhoGEF kinase.
     
 0.721
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.