Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISL1ISL LIM homeobox 1. (349 aa)    
Predicted Functional Partners:
LDB1
LIM domain binding 1.
    
 0.968
LHX4
LIM homeobox 4.
    
 0.947
LHX3
LIM homeobox 3.
    
 0.943
LDB2
LIM domain binding 2.
    
 0.926
GATA4
GATA binding protein 4.
    
 0.836
ENSCWAP00000019346
annotation not available
    
   0.833
ZNF511
Zinc finger protein 511.
    
   0.827
TBX20
T-box transcription factor 20.
   
 0.822
NKX2-5
NK2 homeobox 5.
    
 0.820
PAX6
Paired box 6.
   
 0.816
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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