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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPDL1Spindle apparatus coiled-coil protein 1. (605 aa)    
Predicted Functional Partners:
SKA3
Spindle and kinetochore associated complex subunit 3.
   
 
 0.989
SKA2
Spindle and kinetochore associated complex subunit 2.
   
 
 0.979
NDC80
NDC80 kinetochore complex component.
   
 
 0.966
PLK1
Polo like kinase 1.
   
 
  0.958
CDC20
Cell division cycle 20.
   
 
  0.947
ENSCWAP00000020963
annotation not available
   
 
 0.931
SKA1
Spindle and kinetochore associated complex subunit 1.
   
 
 0.924
CENPF
Centromere protein F.
   
 
 0.917
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.842
CEP55
Centrosomal protein 55.
   
  
 0.840
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.