STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4859 aa)    
Predicted Functional Partners:
BRCA1
BRCA1 DNA repair associated.
    
 0.915
ENSCWAP00000004417
annotation not available
    
 
 0.899
UBE3A
Ubiquitin protein ligase E3A.
   
 0.890
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.889
TP53
Tumor protein p53.
   
 
 0.879
MAPK6
Mitogen-activated protein kinase 6.
    
 
 0.854
NCOA4
Nuclear receptor coactivator 4.
    
 
 0.854
CEP170
Centrosomal protein 170.
    
 
 0.839
USP16
Ubiquitin specific peptidase 16.
    
 
 0.833
RPA1
Replication protein A1.
    
   0.832
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.