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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1RB transcriptional corepressor 1. (929 aa)    
Predicted Functional Partners:
E2F1
E2F transcription factor 1.
   
 0.999
CDK4
Cyclin dependent kinase 4.
   
 0.998
CDK2
Cyclin dependent kinase 2.
   
 0.996
E2F2
E2F transcription factor 2.
   
 0.995
CCND1
Cyclin D1.
    
 0.994
TFDP1
Transcription factor Dp-1.
   
 0.994
MDM2
MDM2 proto-oncogene.
    
 0.992
CDK6
Cyclin dependent kinase 6.
   
 0.989
E2F4
E2F transcription factor 4.
   
 0.989
TFDP2
Transcription factor Dp-2.
   
 0.988
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.