STING1 protein (Catagonus wagneri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

STING1

Stimulator of interferon response cGAMP interactor 1. (375 aa)

Predicted Functional Partners:

TBK1

0.998

IKBKE

0.997

IRF3

0.995

TRIM32

0.995

DDX41

0.989

MNDA

0.979

ENSCWAP00000021159

0.979

TRAF3

0.951

TRIM56

0.944

MAVS

0.939

Your Current Organism:

Catagonus wagneri

NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX41	ENSCWAP00000021159	ENSCWAP00000001663	ENSCWAP00000021159	DEAD-box helicase 41.	annotation not available	0.680
DDX41	IKBKE	ENSCWAP00000001663	ENSCWAP00000013106	DEAD-box helicase 41.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.648
DDX41	IRF3	ENSCWAP00000001663	ENSCWAP00000008547	DEAD-box helicase 41.	Interferon regulatory factor 3.	0.846
DDX41	MAVS	ENSCWAP00000001663	ENSCWAP00000021185	DEAD-box helicase 41.	Mitochondrial antiviral signaling protein.	0.551
DDX41	MNDA	ENSCWAP00000001663	ENSCWAP00000021140	DEAD-box helicase 41.	Myeloid cell nuclear differentiation antigen.	0.680
DDX41	STING1	ENSCWAP00000001663	ENSCWAP00000002368	DEAD-box helicase 41.	Stimulator of interferon response cGAMP interactor 1.	0.989
DDX41	TBK1	ENSCWAP00000001663	ENSCWAP00000006429	DEAD-box helicase 41.	TANK binding kinase 1.	0.782
DDX41	TRIM32	ENSCWAP00000001663	ENSCWAP00000019884	DEAD-box helicase 41.	Tripartite motif containing 32.	0.675
DDX41	TRIM56	ENSCWAP00000001663	ENSCWAP00000021069	DEAD-box helicase 41.	Tripartite motif containing 56.	0.688
ENSCWAP00000021159	DDX41	ENSCWAP00000021159	ENSCWAP00000001663	annotation not available	DEAD-box helicase 41.	0.680
ENSCWAP00000021159	IRF3	ENSCWAP00000021159	ENSCWAP00000008547	annotation not available	Interferon regulatory factor 3.	0.499
ENSCWAP00000021159	STING1	ENSCWAP00000021159	ENSCWAP00000002368	annotation not available	Stimulator of interferon response cGAMP interactor 1.	0.979
ENSCWAP00000021159	TBK1	ENSCWAP00000021159	ENSCWAP00000006429	annotation not available	TANK binding kinase 1.	0.473
IKBKE	DDX41	ENSCWAP00000013106	ENSCWAP00000001663	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	DEAD-box helicase 41.	0.648
IKBKE	IRF3	ENSCWAP00000013106	ENSCWAP00000008547	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Interferon regulatory factor 3.	0.998
IKBKE	MAVS	ENSCWAP00000013106	ENSCWAP00000021185	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Mitochondrial antiviral signaling protein.	0.602
IKBKE	STING1	ENSCWAP00000013106	ENSCWAP00000002368	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Stimulator of interferon response cGAMP interactor 1.	0.997
IKBKE	TBK1	ENSCWAP00000013106	ENSCWAP00000006429	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TANK binding kinase 1.	0.997
IKBKE	TRAF3	ENSCWAP00000013106	ENSCWAP00000009634	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TNF receptor associated factor 3.	0.997
IRF3	DDX41	ENSCWAP00000008547	ENSCWAP00000001663	Interferon regulatory factor 3.	DEAD-box helicase 41.	0.846