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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKCRK proto-oncogene, adaptor protein. (304 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.997
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.996
DOCK1
Dedicator of cytokinesis 1.
    
 0.992
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.991
PTK2
Protein tyrosine kinase 2.
    
 0.989
PXN
Paxillin.
    
 0.989
DOCK5
Dedicator of cytokinesis 5.
    
 0.987
GAB1
GRB2 associated binding protein 1.
    
 0.985
EGFR
Epidermal growth factor receptor.
    
 0.985
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase.
    
0.984
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.