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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (948 aa)    
Predicted Functional Partners:
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
0.942
HTT
Huntingtin.
    
 0.921
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.856
CD247
CD247 molecule.
   
 0.801
TRAF6
TNF receptor associated factor 6.
    
 0.772
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 0.751
MAP2K4
Mitogen-activated protein kinase kinase 4.
   
0.745
TRADD
TNFRSF1A associated via death domain.
   
 0.728
CDC42
Cell division cycle 42.
   
 0.727
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.712
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.