Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIAH1Siah E3 ubiquitin protein ligase 1. (313 aa)    
Predicted Functional Partners:
CACYBP
Calcyclin binding protein.
    
 0.998
CTNNB1
Catenin beta 1.
    
 0.997
SNCA
Synuclein alpha.
    
 0.983
UBE2D1
Ubiquitin conjugating enzyme E2 D1.
    
 0.976
GAPDH
Glyceraldehyde-3-phosphate dehydrogenase.
    
 
 0.972
HIPK2
Homeodomain interacting protein kinase 2.
    
 
 0.970
SIAH2
Siah E3 ubiquitin protein ligase 2.
    
 0.952
USP19
Ubiquitin specific peptidase 19.
    
 
 0.949
DLD
Dihydrolipoamide dehydrogenase.
    
   0.946
AXIN2
Axin 2.
    
 0.940
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.