Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSEN2Presenilin 2. (448 aa)    
Predicted Functional Partners:
PSEN1
Presenilin 1.
  
0.999
ENSCWAP00000006255
annotation not available
    
 0.998
NCSTN
Nicastrin.
   
 0.998
APH1B
Aph-1 homolog B, gamma-secretase subunit.
   
 0.995
APH1A
Aph-1 homolog A, gamma-secretase subunit.
   
 0.994
NOTCH1
Notch receptor 1.
    
 0.981
CTNNB1
Catenin beta 1.
    
 0.980
APP
Amyloid beta precursor protein.
    
 
 0.972
ENSCWAP00000009679
annotation not available
    
 0.961
GSK3B
Glycogen synthase kinase 3 beta.
    
 0.961
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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