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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP1poly(ADP-ribose) polymerase 1. (1018 aa)    
Predicted Functional Partners:
CASP3
Caspase 3.
    
 0.995
PARG
poly(ADP-ribose) glycohydrolase.
    
 0.993
CASP7
Caspase 7.
    
 0.981
PARP2
poly(ADP-ribose) polymerase 2.
  
0.980
CASP9
Caspase 9.
    
 0.975
HPF1
Histone PARylation factor 1.
    
 
 0.955
POLB
DNA polymerase beta.
    
 0.954
SMAD4
SMAD family member 4.
     
 0.954
TIMELESS
Timeless circadian regulator.
   
 
 0.949
XRCC1
X-ray repair cross complementing 1.
    
 
 0.947
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.