Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WWOXWW domain containing oxidoreductase. (414 aa)    
Predicted Functional Partners:
TFAP2C
Transcription factor AP-2 gamma.
    
 0.961
TP53
Tumor protein p53.
    
 
 0.958
FAM189B
Family with sequence similarity 189 member B.
    
 
 0.948
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.936
ERBB4
Erb-b2 receptor tyrosine kinase 4.
    
 0.936
TP73
Tumor protein p73.
    
 
 0.912
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.879
MAPK10
Mitogen-activated protein kinase 10.
   
 
 0.878
EGFR
Epidermal growth factor receptor.
    
 0.877
HADHA
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha.
   
 0.875
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
Server load: low (22%) [HD]