Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.998
RBX1
Ring-box 1.
    
 0.997
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
    
 0.996
UVSSA
UV stimulated scaffold protein A.
    
 0.992
CUL4A
Cullin 4A.
    
 0.988
COPS2
COP9 signalosome subunit 2.
    
 0.985
COPS5
COP9 signalosome subunit 5.
   
  0.982
CUL4B
Cullin 4B.
    
 0.981
COPS3
COP9 signalosome subunit 3.
    
  0.981
GPS1
G protein pathway suppressor 1.
    
  0.978
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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