Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NUMBLNUMB like endocytic adaptor protein. (765 aa)    
Predicted Functional Partners:
NOTCH1
Notch receptor 1.
    
 0.988
NOTCH3
Notch receptor 3.
    
 0.968
AP2A1
Adaptor related protein complex 2 subunit alpha 1.
    
 0.963
NOTCH4
Notch receptor 4.
    
 0.960
NOTCH2
Notch receptor 2.
    
 0.958
ITCH
Itchy E3 ubiquitin protein ligase.
    
 0.955
ENSCWAP00000010514
annotation not available
    
 0.924
GAK
Cyclin G associated kinase.
   
 
 0.917
NUMB
NUMB endocytic adaptor protein.
     
  0.890
TP53
Tumor protein p53.
    
 
 0.889
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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